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In addition, we did not conduct metabolite analysis in tissues, especially in target organs, owing to the small sample size

In published preclinical work, KPV has been studied for inhibiting NF-B activation in intestinal epithelial cells, with one widely cited study showing PepT1-mediated transport into colonic cells as part of its anti-inflammatory mechanism in mouse colitis models (Dalmasso et al., Gastroenterology , 2008)

however, clinical trials in humans are very limited

My sleep disappeared completely after 3rd dosage and when I told doctor about the side effects, he thought I am crazy