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The common dosage that is found to be effective is 1mg to 1.7mg, while some individuals stay at even lower doses and some increase to the max dose of 2.4mg

Efficacy This is where the two medications diverge most significantly

Both contain semaglutide but are formulated and dosed differently based on their indications

Currently, injectable GLP-1s tend to produce stronger and more consistent appetite suppression compared to oral versions

The overall timeline to meaningful results should not change substantially with split dosing since total drug exposure remains equivalent

Unlike semaglutide , which acts as a single GLP-1 receptor agonist, or tirzepatide , which targets both GLP-1 and GIP receptors, retatrutide is a triple agonist