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This phase does correspond well to the second phase (first oxidation phase) observed in the 455 nm traces, confirming that reoxidation of the FAD and formation of the thiolate-FAD charge transfer absorption occur concomitantly, establishing that deprotonation of C159 remains rapid

Proposed axes such as lung-heart ferroptotic coupling are intriguing but currently rest largely on correlative in vivo imaging, inflammatory signaling, and systemic oxidative stress markers rather than direct causal relay experiments

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Exosomal miR-4449 derived from DKD patient serum substantially accelerates tubular epithelial cell pyroptosis and oxidative stress through the transcriptional suppression of HIC1, leading to GSDMD-mediated pore formation and inflammatory cytokine secretion (167)

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A multinational trial of prasugrel for sickle cell vaso-occlusive events