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Some prescribers use twice-daily dosing (splitting the total daily dose), while others prefer a single daily injection
Clinical features such as fatigue, paraesthesia, glossitis, and cognitive changes support the diagnosis
It purportedly works by modulating multiple growth and repair pathways, including angiogenesis (the formation of new blood vessels), fibroblast activation, nitric oxide signalling, and anti-inflammatory cascades, all of which are essential to the healing process
The details are included in B12 Supplementation Trials, but the baseline parameters were such outliers, and the response to treatment was so drastic, that the lines didnt fit in the charts
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