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The 2 major incretins found in the body are gastric-inhibitory-polypeptide (GIP) and glucagon-like-peptide-1 (GLP-1) [2]
These effects drive inflammatory processes and nitro-oxidative pathways [100] and the resultant excess of reactive oxygen species may induce oxidative damage, aggravating systemic tissue damage and contributing to more severe COVID-19 [101]
This dual effect means that maintaining muscle mass is a key concern for menopausal women using GLP-1 medications
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