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Based on the analysis of the literature on the mitochondrial Ca 2+ regulation in cyclophilin D (SypD)-deficient mice and neurons, Rizzuto et al

For instance, early case-control analyses yielded both positive and inverse associations, while more recent pooled analyses suggested only borderline increased risk 278,279,280

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This diminished vasodilator response is correlated with left ventricular diastolic dysfunction [26]

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