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Turner NC, Swift C, Jenkins B, Kilburn L, Coakley M, Beaney M, et al
Given the importance of NLRP3 inflammasome in the pathogenesis of fibrotic disease, the antifibrotic effects of GLP-1R could partially be attributed to its inhibitory potential against NLRP3 inflammasome activation
PubMed Central , Grub, Jessica, et al
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Thus, the spectrum to consider is expansive, including Glu from GLP-1, Asp similar to Glu from GIP, Ala, and even Leu/Ile/Val (forming a hydrophobic area along with Phe 22 )
Calalb MB, Polte TR, Hanks SK
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