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When you use other blood sugar-lowering medications such as sulfonylureas, metformin, or insulin, the risk of hypoglycemia increases significantly
The first incretin-based treatment regimen to be approved for the management of overweight and obesity was liraglutide 3.0 mg once-daily, which was followed by semaglutide 2.4 mg once weekly [16]
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Semaglutide alters appetite, gastric emptying, and metabolic signaling, and these shifts translate into measurable improvements in glucose control, lipids, hydration, and, in some cases, liver or kidney markers
These can lead to dehydration, which may affect blood pressure readings and kidney function
What sets it apart is that it targets three different hormonal pathways in the body GLP-1, GIP, and glucagon receptors that are responsible for hunger, fat metabolism, and energy use
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