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PatchMD is the oldest transdermal supplement brand in the category (they also sell B12 patches, multivitamin patches) and positions their "GLP-1 Support Patch" as part of a wellness lineup, not a standalone weight-loss product

Cardiovascular Health and Insulin Sensitivity L-Carnitine, particularly in its acetyl-L-carnitine (ALCAR) form, demonstrates significant benefits for cardiovascular health and metabolic function through improvement of insulin sensitivity and reduction of cardiovascular risk factors

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Tirzepatide has lower rates of nausea (24-33% vs 43.9%), vomiting (9-13% vs 24.5%), and constipation compared to semaglutide at its weight loss dose

A helpful checkpoint: if your weight is decreasing and your strength is also decreasing, we need to intervene early

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