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Studies have shown that obesity induces increased M1 macrophages (M1) polarization in mice, which may further promote iron deposition, according to in vitro studies (63)
Curr Mol Med (2022) 22(1):3749
doi: 10.1371/journal.pone.0039307 41 ChenMZhaoJ-BWuG-BWuZ-HLuoG-QZhaoZ-Fet al
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An investigation into the effects of a curcumin extract (curcugen()) on osteoarthritis pain of the knee: a randomised, double-blind, placebo-controlled study
The 4-week off-cycle is a recovery period, not a maintenance period
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