Clinical trial results for oral GLP-1 medications have been encouraging
Wall, C
The reasons are multifactorial: chronic inflammation damages blood vessel walls, corticosteroid use raises cholesterol and blood pressure, lupus-specific antibodies (particularly antiphospholipid antibodies) increase clotting risk, and the metabolic disruption caused by both the disease and its treatments creates a perfect storm for atherosclerosis
Second, alcohol can lower blood sugar, and combining alcohol with the blood-sugar-lowering effects of tirzepatide, especially shortly after injection, increases the risk of hypoglycemia in susceptible individuals
Endometriotic tissues implanted in the peritoneal space, fallopian tube, and/or on the ovary have proximity to follicles as they grow, and to oocytes, sperm and embryos as they transit through the fallopian tube
The number needed to treat to prevent a worsening HF event was 95 over 1 year and 30 over 4 years