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Protein intake should remain adequate, at minimum 0.8 grams per kilogram of body weight, to preserve lean mass during rapid weight loss

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Growth hormone (GH) and growth hormone secretagogues like ipamorelin have been shown to mitigate the catabolic effects of glucocorticoids on nitrogen balance and urea synthesis in the liver

This means it has a high potential for misuse

6.3 Clinical applications in cardiovascular disease prevention Recent American College of Cardiology/American Heart Association guidelines advocate for the use of GLP-1RAs in patients with T2DM at high risk of atherosclerotic cardiovascular disease (ASCVD), irrespective of well-controlled glucose levels, based on the clinical trials mandated by FDA-issued industry guidelines in December 2008 to assess the cardiovascular effects of new diabetic therapies (247)

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