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Verbanck M, Chen CY, Neale B, Do R
Epitalons appeal lies in its unusually broad mechanistic reach: it can activate telomerase and support telomere maintenance in human cells [12,13,14, 15], modulate gene expression epigenetically by influencing chromatin accessibility and promoter interactions [4], enhance tissue repair in disease contexts such as diabetic retinopathy by reducing oxidative stress and EMT while improving wound healing in retinal cells [16], bolster redox homeostasis by upregulating endogenous antioxidant defenses and lowering DNA-damage markers [1], rebalance immune tone via IL-2 upregulation [17] and shifts in CD4+/CD8+ profiles [18], and even reset circadian biology by tuning core clock genes and melatonin dynamics [19, 20]
Jorsal, T
Nrf2 plays a crucial role in protecting against doxorubicin-induced cardiotoxicity by regulating oxidative stress and autophagy
It is not a drug, medicine, dietary supplement, food additive, or cosmetic
1,3,6 EGT is a versatile scavenger of reactive oxygen and nitrogen species, thereby protecting critical biomolecules, such as DNA, proteins, and lipids, from oxidative damage
