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It is primarily investigated for its regenerative and cytoprotective properties across multiple tissue types, including muscle, tendon, ligament, and gastrointestinal mucosa

The modifications made Dihexa much more bioavailable and durable, allowing it to cross the blood-brain barrier

While this question mentions a different peptide (PT141), the underlying principle is similar: nasal spray offers convenience

Trafficking & selectivity profiling: Researchers may evaluate internalization, desensitization, and pathway-selective responses (assay-dependent)

doi:10.1093/aje/kww212

However, human clinical trials remain scarce