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35 A total of 56 patients was assessed using the ChildPugh criteria and grouped into either normal, mild, moderate, or severe hepatic impairment

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In the ATTAIN-1 phase 3 trial, orforglipron achieved 7.5%, 8.4%, and 11.2% weight loss after 72 weeks of treatment with 6 mg, 12 mg, and 36 mg, respectively, compared to 2.1% with placebo [32]