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For comparison, tirzepatide (Mounjaro, Zepbound) has a slightly lower constipation rate at 14-17% across doses, possibly because the GIP receptor component partially counteracts GLP-1's motility effects in some patients

I have observed here that many 'stop fencing' with their GP and it seems to be the best course of action

10.1016/j.jad.2021.04.031 J Affect Disord

Circadian misalignment increases cardiovascular disease risk factors in humans

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