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The base case, based on the company's prior pattern with tirzepatide, is that filing follows within roughly six months of TRIUMPH-1 topline
Most GLP-1 medications offer flexibility with a 24-hour window around your regular injection time
J Environ Pathol Toxicol Oncol
SURMOUNT-1 (Jastreboff et al., NEJM 2022, n=2,539) showed the same pattern: nausea and diarrhea were highest in the first three months of the 72-week trial and fell significantly by weeks 20 through 24
Gastrointestinal effects dominate the early weeks
Also, get help if you wake at night to use the bathroom for weeks
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