TABLE 2 Characteristics of the action of non-insulin hypoglycaemic drugs
It binds to the GLP-1 receptor and produces effects including reduced appetite, slower gastric emptying, and increased insulin response after meals
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Others: Roche, J&J, Sanofi, and AZ have had GLP-1 efforts (some deprioritized) or new dual/triple agonists in development (e.g., Roches pipeline includes a dual agonist announced in 2024)
A boxed warning is the most serious warning issued by the FDA about potential drug-related dangers