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The pharmacokinetic rationale is questionable given the 5-day half-life, but some users report better side effect tolerance with split dosing
Energy levels often improve as your body gets better at using fat for fuel
doi:10.1351/pac199365061113
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This is particularly important for individuals with conditions that interfere with B12 absorption, such as pernicious anemia, gastrointestinal disorders like celiac disease or Crohns disease, or those who have undergone certain types of gastrointestinal surgery
If you later see a specialist or change providers, you have a clear history of your therapy, which helps guide ongoing care
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