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PLoS One 14 , e0222158 (2019)
Alper J
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Finally, degradation/release pathways depict the release mechanism, where PLGA nanoparticles degrade under high GSH conditions, releasing the drug to exert its therapeutic effect selectively within tumor cells
Studies: The SURPASS clinical trial program, which tested tirzepatide in various dosages, showed that participants lost a significant amount of weight, and many achieved a weight reduction of 15% or more
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