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Currently, there are some cases reported by the FDA and the EMA that link suicidal ideation and treatment with GLP-1 analogues, but in no case has a cause-effect relationship been demonstrated
By contrast, semaglutide alone yielded 14.8% of patients achieving 25% weight loss, and cagrilintide alone yielded 6.5%
Several GLP-1 analogs, among them exendin 4 (EX4
Conclusion Current evidence suggests that semaglutide can lower SBP and DBP, and increasing the dosage can enhance the blood pressure-lowering effect
So the peptide essentially concentrates where it's needed most
Maroun and Rowlands, 2014
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