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Levels of Glp1r mRNA were not different in the kidney or renal artery of Glp1r Tie2+/+ versus Glp1r Tie2/ mice but were markedly reduced in the lung of Glp1r Tie2/ mice, a tissue enriched in ECs (Figure 3, DF)

(March 2023)

Conversely, a portion of uric acid is secreted back into the proximal tubular lumen through various apical transporters, including ABCG2, NPT1, NPT4, and GLUT9, along with the basolateral transporters OAT1 and OAT3