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10.1016/j.jep.2020.112895 9 ChengT
These compounds block the activity of an important enzyme, Tyrosinase which is the main enzyme that produces melanin
One possibility is that diminishment of NADPH also inhibits thioredoxin reductase in the cytosol, and that cytosolic glutathione becomes more oxidized because it must compensate in the reduction of reactive oxygen species for the shortage of reduced thioredoxin
Clinical studies report a 1525% rise in IGF-1 after 36 months of nightly dosing PubMed study on sermorelin and IGF-1
Recent good quality research by Tolbert and Findling found that B6 and magnesium did not result in statistically significant effects
PMID: 1220811 Finkel T, Holbrook NJ
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