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Alpha-lipoic acid interactions: Potentiates insulin, sulfonylureas, and GLP-1 agonists hypoglycemia risk
Moderate deficit works best: 300-500 calorie deficit below maintenance
Another funny tidbit about the fuzzy research is the peptide is most often clinically administered intramuscularly with an injection even though the research suggests the positive effects were noticed when it was given orally (4)
The result looks like accelerated aging
Agarwal S, Muqit MMK (2022) PTEN-induced kinase 1 (PINK1) and Parkin: unlocking a mitochondrial quality control pathway linked to Parkinsons disease
Nature 636 , 206214 (2024)
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