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However, preclinical studies showed that GIP agonism might activate GABAergic neurons in the brainstem, which in turn will hinder GLP-1-induced malaise, aligning with our results. People using tirzepatide were more likely to experience gastrointestinal events compared with those using SGLT2 inhibitors and insulin

doi: 10.1111/jdi.12477 10 HarfmannBDSchroderEAEsserKA

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