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Mechanistically, NNMT suppression increased adipose SAM and NAD, upregulated polyamine flux enzymes (ODC, SSAT), and altered histone methylation consistent with a shift toward oxidative metabolism [2]
Though GHK-Cu delivers minimal copper per dose and the peptide controls copper release, extended use warrants verification that copper homeostasis remains normal
Evid Based Complement Alternat Med (2013) 2013:113
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van der Pol A, van Gilst WH, Voors AA, van der Meer P
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