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Clin Sci (Lond)

Always talk to your doctor about the risks and benefits of any treatment

The duration of use depends on how severe your vitamin deficiencies are and your overall medical condition

But for some users, nausea becomes dose-limiting

Researchers induced knee osteoarthritis in rabbits using collagenase injections, then treated the animals with weekly intra-articular injections of AOD-9604, hyaluronic acid, or a combination of both compounds

Typical conversions from animal studies use body-surface-area scaling: Rat dose: 10 g/kg human equivalent ( 0.162) 1.6 g/kg For a 70 kg adult: ~112 g per day Self-experiment protocols often cite 100200 g once or twice daily via subcutaneous injection