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2017;43(Suppl 1):2S207

Dalva-Aydemir, S

& Elinav, E

Contact your GP or diabetes specialist nurse if you experience : Excessive thirst combined with frequent urination : This may indicate worsening glycaemic control or inadequate diabetes management, requiring blood glucose monitoring and potential treatment adjustment

Fundamentally, GLP-1RAs work by stimulating insulin secretion and inhibiting glucagon secretion in a glucose-dependent manner [9], which explains their associated low risk of hypoglycaemia

Manufacturing capacity is currently limited because only a handful of facilities can produce retatrutide at scale