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The FDA has designated BPC-157 as a Category 2 compound, which indicates concerns over safety and limits compounding under federal regulations

Signal Peptide Activity and Fibroblast Stimulation In-vitro studies on cultured dermal fibroblasts have consistently reported that GHK-Cu exposure at nanomolar to low-micromolar concentrations restores proliferative capacity in senescent or irradiated cells [2][3]