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These basic and translational neuroscience findings point to this mitochondrial signaling pathway as a potential target to identify novel mechanisms of brain plasticity and potential unique targets for therapeutic intervention targeted to specific clinical phenotypes

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It is important to note that patients with a history of major depression were actually excluded from the phase 3 randomized controlled trials (RCTs) of these medications 10,11,12,13,14,15,21,22,23

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Environ Sci Pollut Res 24:2698326987 Nyakayiru J, Jonvik KL, Trommelen J, Pinckaers PJM, Senden JM, Van Loon LJC, Verdijk LB (2017) Beetroot juice supplementation improves high-intensity intermittent type exercise performance in trained soccer players