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6.4 Oxidative stress Oxidative stress plays a critical role in hypertension due to the fundamental roles of ROS and redox signaling in molecular, cellular, and systemic processes that contribute to endothelial injury, vascular dysfunction, cardiovascular remodeling, renal impairment, sympathetic nervous system excitation, immune cell activation, and systemic inflammationkey factors in the pathophysiology of hypertension [240, 241]

BPC-157 is used in cell-based assay research examining its interactions with growth factor receptor signalling pathways, including FAK-paxillin pathway activation and downstream phosphorylation events