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Kromhout D, Geleijnse JM, de Goede J, Oude Griep LM, Mulder BJ, de Boer MJ,

If the product you're evaluating makes claims that sound like medical treatment, assume it's either FDA-approved (which glutathione isn't for most indications) or operating outside regulatory boundaries

Arch Med Res

The effects of the oral supplementation of L-Cystine associated with reduced L-Glutathione-GSH on human skin pigmentation: a randomized, double-blinded, benchmark- and placebo-controlled clinical trial

Essentially, the FDA has not formally evaluated this exact mixture for safety/efficacy, but each ingredients effects are well-known

Selenium Requirements for Peroxidase Performance Glutathione functions through enzyme systems