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Pollution and skin: from epidemiological and mechanistic studies to clinical implications

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The absence of clinical guidelines leaves surgeons navigating an evidence gap with potential medicolegal implications, particularly when patients undergo elective procedures where the acceptable tolerance for unmeasured risk is low

A reduction in experimental lesions may indicate cytoprotection-associated activity in a controlled model, but it does not necessarily explain whether the primary driver is endothelial preservation, anti-inflammatory signaling, epithelial restitution, altered motility, or a combination of these processes

A significant rate of severe jaundice causing kernicterus still plagues much of the world population especially in lower income economies

(2) Modifying the expression of glycolytic and gluconeogenic enzymes