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OTX2 restricts entry to the mouse germline

When taken orally, peptides are notoriously unstable and difficult to deliver to the target location, meaning it would be very unlikely that it would reach the nucleus pulposus directly

The authors concluded that GHK and GHK-Cu increased epidermal cell stemness and keratinocyte proliferation, also increasing p63 and integrin expression [ 48 , 49 ]

A: Yes, topical works well for skin benefits specifically

Environmental and molecular mutagenesis , 58 (2), 6071

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