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The clinical picture is clear on the deficiency side

The proposed mechanism for the GHK-Cu component is copper chemistry rather than receptor pharmacology: delivery or sequestration of copper relevant to copper-dependent enzymes, and reported changes in extracellular-matrix gene expression in cultured cells

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Collagen Production Goes Into Overdrive The headline number is a 70% increase in collagen I production in human dermal fibroblasts at optimal concentrations