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Almahariq, M., Mei, F

The thyroid contains the highest selenium concentration of any organ

The role of the kidney in drug elimination: transport, metabolism, and the impact of kidney disease on drug clearance

Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer

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Introduction Cysteine, a sulfhydryl-containing proteinogenic amino acid essential for the human body, is employed in a variety of metabolic pathways, such as the regulation of reduced glutathione (GSH), a major endogenous antioxidant molecule and the generation of sulfur-containing biomolecules such as hydrogen sulfide (H 2 S), taurine, coenzyme A and biotin ( Figure 1 ) ( Figure 1 Cysteine metabolism in cancer and tumor microenvironment It is increasingly noted that altered levels of amino acids including cysteine in the tumor microenvironment, by uptake or processing of both intracellular and extracellular regions, have emerged as potential markers of tumor progression