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Common formulations include tretinoin (0.0250.1%) paired with clindamycin (1%) and niacinamide (45%)

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Common mild side effects include injection-site irritation or temporary water retention, but serious reactions warrant immediate protocol adjustment or discontinuation

However, peoples impairment lagged far behind, peaking about 5 hours after drinking alcohol even in participants well below the legal limit for driving under the influence (DUI)