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The traditional classification of DM is mainly based on abnormalities in insulin secretion and action, such as type 1 DM due to an absolute lack of insulin secretion and T2DM due to insulin resistance and relative insulin deficiency

By contrast, orforglipron is a small molecule

It measures glucose levels, electrolyte and fluid balance, and kidney and liver function

Intriguingly, in patients with dumping syndrome, postprandial serum catecholamine rises correspond with increased serum GLP-1 levels (184)

However, this is a specialized approach that requires careful medical supervision

Proper injection technique and provider guidance may help reduce discomfort