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Buckley ST et al
The trade-off is cost (significantly higher than vials) and dosing flexibility (pens offer fixed dose increments)
When discussing Wegovy specifically, explain that it is semaglutide, a GLP-1 receptor agonist prescribed for weight management
Physicians must have systems in place for tracking patients over time monitoring for adverse effects, assessing muscle mass changes, evaluating dietary habits, and managing the rebound weight gain that frequently occurs when patients stop the drug
Retatrutide may produce greater overall weight loss because it targets an additional hormone pathway linked to calorie burning and fat metabolism
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