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In vitro experiments suggest that GSH is a poor substrate for Ero1 (Tu & Weissman, 2002)
S., & Das, K
Common examples include fatigue or low energy with normal blood results, brain fog or reduced concentration without confirmed vitamin B12 deficiency, stress-related exhaustion or burnout, increased metabolic demand such as during illness recovery, high workload, or intense training, restrictive or inconsistent dietary intake, or suspected poor oral absorption despite normal serum levels
Depletion of RNF4 exerts antiproliferative effects in AML cells and increased their sensitivity towards antileukemic drugs thus validating RNF4 as a potential vulnerability in AML
Ni Gabhann, J
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