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FDA prescribing information warns that gastrointestinal reactions can lead to dehydration and volume depletion

Avoid alcohol and smoking : Both can aggravate reflux and potentially trigger hiccups

These medicines may be affected by hydroxocobalamin, or may affect how well it works

A., Kain, T

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Five years after reaching the nadir of weight loss, 50.2% of the RYGB patients regained more than 15% of maximal weight loss and 86.5% regained more than 10% of maximal weight loss [3]