GLP-1, first and foremost, is an acronym for a hormone made naturally in our bodies, glucagon-like peptide-1. GLP-1 is secreted by the intestines and has multiple roles in our bodily functions
Semaglutide's weight loss mechanisms work through appetite suppression and reduced caloric intake, not through caloric loss via diarrhea
: Ultimate Nutrition
The other reason to stack is to cover weaknesses in a single-compound protocol
GLP-1 Agonists liraglutide (Saxenda) semaglutide (Wegovy) GIP/GLP-1 Agonist tirzepatide (Zepbound) In addition to helping you lose weight, GLP-1 and dual GIP/GLP-1 agonists can help lower your risk of some conditions that go hand in hand with obesity: type 2 diabetes, heart disease, heart failure, kidney disease, metabolic dysfunctionassociated steatotic liver disease, and obstructive sleep apnea
By slowing down how quickly your stomach empties and improving insulin sensitivity, it helps many people achieve significant weight loss