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Because of the retrospective nature of the study and the use of de-identified data, this study received an exemption waiver for approval and informed consent from the Institutional Review Board (IRB) of Chung Shan Medical University Hospital, identified by the reference number CS1-24047
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Published research on these studies documented outcomes from approximately 900 adult participants, predominantly individuals classified as clinically obese, though one trial included healthy non-obese volunteers
In psychiatric disorders (excluding schizophrenia), clinical studies reported improvements in mood regulation, anxiety reduction, and cognitive performance, possibly mediated by modulation of the gut-brain axis and reduction of systemic inflammation (Hong et al., 2022
This article is general information only and is not intended to diagnose, treat, cure or prevent any disease or medical condition
The bremelanotide-MC4R-Gs complex structure was deposited in the Protein Data Bank under accession number 7F55 and Electron Microscopy Data Bank under accession code 31458, at a resolution of 3.1 ngstrms
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