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TB-500 is a synthetic version of Thymosin Beta-4 , a naturally occurring peptide in humans

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Glutathione is involved in various important liver detoxification processes, amino-acid transport, production of coenzymes, and the recycling of vitamins C and E

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Plasmid for single-stranded adeno-associated viral vectors 2/8 The plasmid pAAV-MCS-hAAT/EGFP was designed for maximum transgene expression and includes the hepatic locus control region from the ApoE gene (ApoE-HCR), a liver-specific 1-antitrypsin promoter (hAAT promoter), coagulation factor IX intron A (FIX intron A), a 3' mRNA transcription termination/polyadenylation signal (bghpA), and a reporter gene encoding enhanced green fluorescent protein (EGFP), as previously described (Miao et al