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Your risk goes up if you already had dry mouth, take other medications that reduce saliva, or have a history of cavities

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This reparative effect is mediated, at least in part, through the upregulation and reorganization of key regulatory proteins, most notably protein kinase C (PKC) and the tight junction scaffolding protein zonula occludens-2 (ZO-2), thereby facilitating the reassembly and functional recovery of the tight junction complex (161)

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Increasing hydration, optimizing protein intake, supplementing electrolytes, rotating injection sites, and slowing dose escalation resolve muscle pain in the majority of cases without requiring discontinuation

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