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Natural flavonoids could be broadly categorized into eight classes based on the degree of hybridization of the intermediate carbon atom and the bonding position of the B-ring (at position 2 or 3), including flavonoids, flavonols, dihydroflavonoids, dihydroflavonols, isoflavones, flavan-3-ols, anthocyanins, and chalcones (e.g., baicalin, gambogic acid, puerarin, Fig

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