Chronic elevation (hypercortisolism or Cushing's syndrome) leads to central obesity, insulin resistance, hypertension, muscle weakness (particularly proximal), wide purple striae, facial plethora, and increased cardiovascular risk
When to Call Your Clinician: Red Flags to Watch For Contact your clinician for persistent, severe dry mouth that causes dehydration, rampant dental cavities, or trouble swallowing
Eli Lillys prescribing information for Mounjaro explicitly recommends switching to a non-oral contraceptive method for 4 weeks after starting Mounjaro and for 4 weeks after each dose increase
Lifestyle Factors That May Support Retatrutide Treatment Evidence-based lifestyle measures including a nutrient-dense diet, resistance and aerobic exercise meeting UK CMO guidelines, improved sleep, stress management, and alcohol reduction are appropriate complements to weight-loss pharmacotherapy
Both Retatrutide and Tirzepatide demonstrate a capacity to promote weight loss, primarily through decreased appetite and improved metabolic function
Optimize Your Results: Consider adding supportive supplements like our GLP-1 Daily Support to help maintain digestive balance and nutrient intake during your program