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The most common adverse events were gastrointestinal in nature and consistent with other incretin-based drugs

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MSCs were seeded at a density of 3 10 4 cells/well into the upper chambers of Transwell inserts (Costar Transwell

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This model, while allowing precise control of the timing of small intestinal exposure to metformin and mitigation of the wide inter-individual variation in the rate of gastric emptying [29, 30], is somewhat unphysiological