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ACSL4 acylates AA, and subsequently, LPCAT3 catalyzes the acylated AA to membrane PL, which raises the oxidation of membrane-sensitive fatty acids such as PUFA, ultimately leading to lipid peroxidation [73]
Il agit subtilement, dans la dure, et surtout en synergie
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Gamma-oryzanol, a molecule derived from rice bran oil, has been shown to inhibit ferroptosis and cartilage degradation by engaging with the Keap1 and Nrf2 binding sites in IL-1-treated chondrocytes [108]
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