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6 They activate mitogen-activated protein kinase (MAPK) pathways that induce key regulators in late G1 phase such as Cyclin Ds and cyclin-dependent-kinases 4/6 (CDKs), which have a critical role in the control of the G1/S transition and the commitment to DNA replication
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The study excluded individuals who consumed alcohol or caffeine beyond recommended daily limits, those who smoked, were pregnant or lactating, had used supplements or energy drinks with taurine or B vitamins in the 30 days before enrollment, or suffered from sleep disorders
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